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Monoclonal Antibodies

Monoclonal Antibodies
TC cells are important in controlling

virus infections
all of these
autoimmunity
allergy

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Monoclonal Antibodies
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

presence of HAMA response
poor recognition of immunoglobulin, Ig constant regions
All of these
absence of human immune response against murine proteins (HAMA) response

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Monoclonal Antibodies
The Ig locus is about

l/2nd of all hybridomas
1/4th of all hybridomas
2/3rd of all hybridomas
l/3rd of all hybridomas

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

Transfection with tumor derived DNA
All of these
Transformation following infection by Epstein-Barr virus (EB V)
Hybridization with a suitable lymphoid tumor cell

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Monoclonal Antibodies
In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a

natural killer cell
hybridoma
lymphoblast
myeloma

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Monoclonal Antibodies
A cytokine that stimulates the activity of B and T cells is

interlukin-2
interlukin-1
all of these
lymphotoxin

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