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Monoclonal Antibodies

Monoclonal Antibodies
The primary B cell receptor is

IgG
IgE
IgA
IgD

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

All of these
Transformation following infection by Epstein-Barr virus (EB V)
Transfection with tumor derived DNA
Hybridization with a suitable lymphoid tumor cell

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Monoclonal Antibodies
The EBV-hybridoma technique

All of these
gives much higher hybridization frequencies
immortalizes the donor Bcells
facilitates the proliferation of antigen specific B cells

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Monoclonal Antibodies
The hybrid cells can be propagated

both (a) and (b)
none of these
in tissue culture
as ascites in peritoneal cavity of mice

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Monoclonal Antibodies
In human B cells and T cells are matured in the

bone marrow and thymus respectively
bursa and thymus respectively
lymph nodes and spleen respectively
none of these

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Monoclonal Antibodies
TC cells are important in controlling

virus infections
autoimmunity
all of these
allergy

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