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Monoclonal Antibodies

Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgG
IgA
IgE
Ig MAbs

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Monoclonal Antibodies
The hybrid cells can be propagated

as ascites in peritoneal cavity of mice
both (a) and (b)
in tissue culture
none of these

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Monoclonal Antibodies
An example of mosaic antigen is

bacteria
virus
a hapten
protein

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Monoclonal Antibodies
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

high frequencies
at no frequency
moderate frequencies
low frequencies

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Monoclonal Antibodies
Which type of cell actually secrets antibodies?

plasma cells
T cells
macrophages
dendritic cells

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Monoclonal Antibodies
Small simple molecules are

poor antigens
moderate antigens
heterophilic antigens
rich antigens

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