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Monoclonal Antibodies

Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgA
IgG
IgE
Ig MAbs

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Monoclonal Antibodies
In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a

natural killer cell
lymphoblast
hybridoma
myeloma

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Monoclonal Antibodies
The hybrid cells can be propagated

none of these
both (a) and (b)
as ascites in peritoneal cavity of mice
in tissue culture

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Monoclonal Antibodies
An example of mosaic antigen is

protein
a hapten
bacteria
virus

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Monoclonal Antibodies
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

poor recognition of immunoglobulin, Ig constant regions
presence of HAMA response
All of these
absence of human immune response against murine proteins (HAMA) response

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Monoclonal Antibodies
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

high frequencies
at no frequency
low frequencies
moderate frequencies

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