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Monoclonal Antibodies

Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgG
Ig MAbs
IgA
IgE

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Monoclonal Antibodies
A cytokine that stimulates the activity of B and T cells is

interlukin-1
all of these
interlukin-2
lymphotoxin

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Monoclonal Antibodies
In human B cells and T cells are matured in the

lymph nodes and spleen respectively
none of these
bone marrow and thymus respectively
bursa and thymus respectively

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Monoclonal Antibodies
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

low frequencies
moderate frequencies
at no frequency
high frequencies

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Monoclonal Antibodies
The cross linkage of antigens by antibodies is known as

agglutination
a cross reaction
complement fixation
all of these

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Monoclonal Antibodies
The EBV-hybridoma technique

immortalizes the donor Bcells
gives much higher hybridization frequencies
facilitates the proliferation of antigen specific B cells
All of these

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