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Monoclonal Antibodies

Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgA
Ig MAbs
IgE
IgG

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Monoclonal Antibodies
T cells are the source of

all of these
interferon
lymphotoxin
interleukin

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Monoclonal Antibodies
A cytokine that stimulates the activity of B and T cells is

all of these
interlukin-2
lymphotoxin
interlukin-1

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Monoclonal Antibodies
The primary B cell receptor is

IgE
IgA
IgG
IgD

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Monoclonal Antibodies
The EBV-hybridoma technique

immortalizes the donor Bcells
facilitates the proliferation of antigen specific B cells
All of these
gives much higher hybridization frequencies

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Monoclonal Antibodies
In human B cells and T cells are matured in the

bursa and thymus respectively
lymph nodes and spleen respectively
none of these
bone marrow and thymus respectively

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