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Monoclonal Antibodies

Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgG
IgA
IgE
Ig MAbs

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

Transformation following infection by Epstein-Barr virus (EB V)
All of these
Transfection with tumor derived DNA
Hybridization with a suitable lymphoid tumor cell

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Monoclonal Antibodies
The Ig locus is about

l/2nd of all hybridomas
1/4th of all hybridomas
2/3rd of all hybridomas
l/3rd of all hybridomas

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Monoclonal Antibodies
In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

T8 cells are greatly reduced
T4 cells are greatly increased
T4 cells are greatly reduced
T8 cells are greatly increased

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Monoclonal Antibodies
The hybrid cells can be propagated

in tissue culture
as ascites in peritoneal cavity of mice
both (a) and (b)
none of these

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Monoclonal Antibodies
The primary B cell receptor is

IgD
IgA
IgE
IgG

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