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Monoclonal Antibodies

Monoclonal Antibodies
A cytokine that stimulates the activity of B and T cells is

lymphotoxin
interlukin-2
interlukin-1
all of these

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

Transfection with tumor derived DNA
Hybridization with a suitable lymphoid tumor cell
Transformation following infection by Epstein-Barr virus (EB V)
All of these

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Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

Ig MAbs
IgG
IgA
IgE

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Monoclonal Antibodies
Which type of cell actually secrets antibodies?

dendritic cells
T cells
plasma cells
macrophages

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Monoclonal Antibodies
The hybrid cells can be propagated

in tissue culture
both (a) and (b)
as ascites in peritoneal cavity of mice
none of these

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Monoclonal Antibodies
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

high frequencies
at no frequency
moderate frequencies
low frequencies

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