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Monoclonal Antibodies

Monoclonal Antibodies
T cells are the source of

all of these
interferon
lymphotoxin
interleukin

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Monoclonal Antibodies
The Ig locus is about

l/3rd of all hybridomas
l/2nd of all hybridomas
2/3rd of all hybridomas
1/4th of all hybridomas

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Monoclonal Antibodies
The cross linkage of antigens by antibodies is known as

a cross reaction
agglutination
all of these
complement fixation

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Monoclonal Antibodies
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

moderate frequencies
high frequencies
at no frequency
low frequencies

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Monoclonal Antibodies
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

All of these
absence of human immune response against murine proteins (HAMA) response
presence of HAMA response
poor recognition of immunoglobulin, Ig constant regions

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Monoclonal Antibodies
The EBV-hybridoma technique

immortalizes the donor Bcells
gives much higher hybridization frequencies
facilitates the proliferation of antigen specific B cells
All of these

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