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Monoclonal Antibodies

Monoclonal Antibodies
Small simple molecules are

moderate antigens
rich antigens
heterophilic antigens
poor antigens

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Monoclonal Antibodies
The primary B cell receptor is

IgA
IgE
IgD
IgG

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Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgA
Ig MAbs
IgG
IgE

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Monoclonal Antibodies
In human B cells and T cells are matured in the

bursa and thymus respectively
bone marrow and thymus respectively
lymph nodes and spleen respectively
none of these

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Monoclonal Antibodies
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

presence of HAMA response
poor recognition of immunoglobulin, Ig constant regions
absence of human immune response against murine proteins (HAMA) response
All of these

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Monoclonal Antibodies
In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

T4 cells are greatly increased
T8 cells are greatly reduced
T4 cells are greatly reduced
T8 cells are greatly increased

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