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Monoclonal Antibodies

Monoclonal Antibodies
The cross linkage of antigens by antibodies is known as

complement fixation
agglutination
a cross reaction
all of these

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Monoclonal Antibodies
In human B cells and T cells are matured in the

lymph nodes and spleen respectively
bone marrow and thymus respectively
bursa and thymus respectively
none of these

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Monoclonal Antibodies
The Ig locus is about

1/4th of all hybridomas
2/3rd of all hybridomas
l/2nd of all hybridomas
l/3rd of all hybridomas

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Monoclonal Antibodies
The EBV-hybridoma technique

facilitates the proliferation of antigen specific B cells
gives much higher hybridization frequencies
immortalizes the donor Bcells
All of these

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

All of these
Hybridization with a suitable lymphoid tumor cell
Transfection with tumor derived DNA
Transformation following infection by Epstein-Barr virus (EB V)

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Monoclonal Antibodies
In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

T8 cells are greatly reduced
T8 cells are greatly increased
T4 cells are greatly reduced
T4 cells are greatly increased

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