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Monoclonal Antibodies

Monoclonal Antibodies
The cross linkage of antigens by antibodies is known as

agglutination
all of these
complement fixation
a cross reaction

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

Hybridization with a suitable lymphoid tumor cell
Transformation following infection by Epstein-Barr virus (EB V)
Transfection with tumor derived DNA
All of these

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Monoclonal Antibodies
The hybrid cells can be propagated

none of these
as ascites in peritoneal cavity of mice
in tissue culture
both (a) and (b)

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Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgA
IgG
IgE
Ig MAbs

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Monoclonal Antibodies
Helper T cells assist in the functions of

certain B cells and other T cells
certain T cells
None of these
certain B cells

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Monoclonal Antibodies
In human B cells and T cells are matured in the

bone marrow and thymus respectively
none of these
lymph nodes and spleen respectively
bursa and thymus respectively

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