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Monoclonal Antibodies

Monoclonal Antibodies
The cross linkage of antigens by antibodies is known as

agglutination
complement fixation
all of these
a cross reaction

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Monoclonal Antibodies
The EBV-hybridoma technique

gives much higher hybridization frequencies
immortalizes the donor Bcells
All of these
facilitates the proliferation of antigen specific B cells

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Monoclonal Antibodies
In human B cells and T cells are matured in the

bone marrow and thymus respectively
bursa and thymus respectively
none of these
lymph nodes and spleen respectively

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

All of these
Transfection with tumor derived DNA
Hybridization with a suitable lymphoid tumor cell
Transformation following infection by Epstein-Barr virus (EB V)

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Monoclonal Antibodies
Which type of cell actually secrets antibodies?

macrophages
plasma cells
dendritic cells
T cells

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Monoclonal Antibodies
Small simple molecules are

heterophilic antigens
rich antigens
poor antigens
moderate antigens

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