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Monoclonal Antibodies

Monoclonal Antibodies
An example of mosaic antigen is

virus
protein
a hapten
bacteria

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Monoclonal Antibodies
The hybrid cells can be propagated

in tissue culture
none of these
both (a) and (b)
as ascites in peritoneal cavity of mice

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Monoclonal Antibodies
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

presence of HAMA response
All of these
absence of human immune response against murine proteins (HAMA) response
poor recognition of immunoglobulin, Ig constant regions

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Monoclonal Antibodies
Small simple molecules are

moderate antigens
poor antigens
rich antigens
heterophilic antigens

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Monoclonal Antibodies
In human B cells and T cells are matured in the

none of these
lymph nodes and spleen respectively
bone marrow and thymus respectively
bursa and thymus respectively

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Monoclonal Antibodies
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

high frequencies
moderate frequencies
low frequencies
at no frequency

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