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Structure and Properties of Peptides

Structure and Properties of Peptides
Which of the following is an example of tertiary structure in a protein?

A multimeric protein
A P-pleated sheet
A globular domain
An a-helix

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Structure and Properties of Peptides
The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce

Val-Lys-Glu-Met + Ser-Trp-Arg-Ala.
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.

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Structure and Properties of Peptides
Disulfide bonds most often stabilize the native structure of

extracellular proteins
intracellular proteins
dimeric proteins
hydrophobic proteins

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Structure and Properties of Peptides
The nature of peptide bond can be best explained as

truly double bond
partial double bond
Hydrogen bond
Van der waals force

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Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

globular proteins
fibrous proteins
collagen
silk protein

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

have Y = F = 180°
do not occur in nature
are equivalent to the (3-sheet structure
also have a cis geometry in their peptide bonds

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