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Structure and Properties of Peptides

Structure and Properties of Peptides
Which of the following is an example of tertiary structure in a protein?

A P-pleated sheet
A multimeric protein
A globular domain
An a-helix

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Structure and Properties of Peptides
If the F and Y angles of each peptide unit in a protein are known, which of the following may also be determined?

Thermodynamic stability
Complete quaternary structure
Complete tertiary structure
Complete secondary structure

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Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

silk protein
fibrous proteins
globular proteins
collagen

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Structure and Properties of Peptides
Hydrogen bonds in a-helices are

roughly parallel to the helix axis
analogous to the steps in a spiral staircase
not present at Phe residues
more numerous than Vander Waals interactions

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

are equivalent to the (3-sheet structure
also have a cis geometry in their peptide bonds
do not occur in nature
have Y = F = 180°

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

No effect on oxygen affinity
Increase in oxygen affinity
Increase affinity in muscle cell otherwise decrease
Decrease in oxygen affinity

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