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Structure and Properties of Peptides

Structure and Properties of Peptides
Which of the following is an example of tertiary structure in a protein?

An a-helix
A P-pleated sheet
A globular domain
A multimeric protein

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Structure and Properties of Peptides
The oxygen in hemoglobin and myoglobin is bound to

the iron atom in the heme group
histidine residues in the protein
lysine residues in the protein
the nitrogen atoms on the heme

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

do not occur in nature
also have a cis geometry in their peptide bonds
have Y = F = 180°
are equivalent to the (3-sheet structure

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Structure and Properties of Peptides
The resonance structures that can be drawn for the peptide bond indicate that the peptide bond

is still not completely understood
both (a) and (b)
has partial double bond character
is stronger than an ordinary single bond

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Structure and Properties of Peptides
Heme is the binding pocket of myoglobin and hemoglobin and is composed of

hydrophobic residues
polar residues
positively charged residues
negatively charged residues

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Structure and Properties of Peptides
In the β-pleated sheet

hydrogen bonds are formed between the peptide bonds
All of these
adjacent polypeptide chains can either be parallel or antiparallel
the polypeptide chain is fully extended

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