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Structure and Properties of Peptides

Structure and Properties of Peptides
What is the proportion of glycine residues in collagenous regions?

One-fourth
Half
One-tenth
One-third

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Structure and Properties of Peptides
The peptide bond in proteins is

only found between proline residues
is planar because of steric hinderance
usually cis unless proline is the next amino acid
usually trans unless proline is the next amino acid

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Structure and Properties of Peptides
The peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala, was digested with cyanogen bromide (CNBr) to produce:

Val-Lys-Glu-Met + Ser-Trp-Arg-Ala
Val-Lys-Glu + Met-Ser-Trp-Arg-Ala
Val-Lys-Glu-Met-Ser-Trp + Arg-Ala
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala

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Structure and Properties of Peptides
The resonance structures that can be drawn for the peptide bond indicate that the peptide bond

both (a) and (b)
is still not completely understood
is stronger than an ordinary single bond
has partial double bond character

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

Increase affinity in muscle cell otherwise decrease
Increase in oxygen affinity
No effect on oxygen affinity
Decrease in oxygen affinity

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

have Y = F = 180°
are equivalent to the (3-sheet structure
do not occur in nature
also have a cis geometry in their peptide bonds

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