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Structure and Properties of Peptides

Structure and Properties of Peptides
Heme is the binding pocket of myoglobin and hemoglobin and is composed of

hydrophobic residues
positively charged residues
polar residues
negatively charged residues

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Structure and Properties of Peptides
The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce

Val-Lys-Glu-Met + Ser-Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.

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Structure and Properties of Peptides
The nature of peptide bond can be best explained as

partial double bond
Hydrogen bond
Van der waals force
truly double bond

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Structure and Properties of Peptides
In β-pleated sheet structures neighbouring

neighboring chains are connected by a-helices
neighboring chains are hydrogen bonded
neighboring residues are hydrogen bonded
chains lie in a flat plane

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Structure and Properties of Peptides
The oxygen in hemoglobin and myoglobin is bound to

the nitrogen atoms on the heme
the iron atom in the heme group
lysine residues in the protein
histidine residues in the protein

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Myoglobin
Pancreatic DNase
Pancreatic ribonuclease
Lysozyme

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