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Structure and Properties of Peptides

Structure and Properties of Peptides
Heme is the binding pocket of myoglobin and hemoglobin and is composed of

polar residues
positively charged residues
negatively charged residues
hydrophobic residues

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Structure and Properties of Peptides
The peptide bond in proteins is

usually cis unless proline is the next amino acid
is planar because of steric hinderance
usually trans unless proline is the next amino acid
only found between proline residues

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Structure and Properties of Peptides
The resonance structures that can be drawn for the peptide bond indicate that the peptide bond

has partial double bond character
is still not completely understood
is stronger than an ordinary single bond
both (a) and (b)

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Structure and Properties of Peptides
The heme is held in place by a bond between

the Fe3+ and histidine
the Fe2+ and cysteine
the Fe2+ and histidine
the Fe3+ and cysteine

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Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

collagen
globular proteins
fibrous proteins
silk protein

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Structure and Properties of Peptides
When pO2 = Kd of myoglobin, the fractional saturation (YO2) is about

1.7
0.5
0.1
0.9

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