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Structure and Properties of Peptides

Structure and Properties of Peptides
Heme is the binding pocket of myoglobin and hemoglobin and is composed of

positively charged residues
polar residues
hydrophobic residues
negatively charged residues

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Structure and Properties of Peptides
The resonance structures that can be drawn for the peptide bond indicate that the peptide bond

both (a) and (b)
is stronger than an ordinary single bond
has partial double bond character
is still not completely understood

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Structure and Properties of Peptides
In the β-pleated sheet

hydrogen bonds are formed between the peptide bonds
All of these
adjacent polypeptide chains can either be parallel or antiparallel
the polypeptide chain is fully extended

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Structure and Properties of Peptides
Which hemoglobin chain replaces the beta chain in embryonic hemoglobulin?

Gamma
Epsilon
Alfa
Delta

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Structure and Properties of Peptides
The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce

Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met + Ser-Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Pancreatic ribonuclease
Lysozyme
Myoglobin
Pancreatic DNase

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