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Structure and Properties of Peptides

Structure and Properties of Peptides
Heme is the binding pocket of myoglobin and hemoglobin and is composed of

polar residues
positively charged residues
hydrophobic residues
negatively charged residues

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Structure and Properties of Peptides
The resonance structures that can be drawn for the peptide bond indicate that the peptide bond

has partial double bond character
is stronger than an ordinary single bond
both (a) and (b)
is still not completely understood

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

No effect on oxygen affinity
Increase affinity in muscle cell otherwise decrease
Increase in oxygen affinity
Decrease in oxygen affinity

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Pancreatic DNase
Myoglobin
Lysozyme
Pancreatic ribonuclease

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Structure and Properties of Peptides
The heme is held in place by a bond between

the Fe2+ and cysteine
the Fe3+ and cysteine
the Fe2+ and histidine
the Fe3+ and histidine

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Structure and Properties of Peptides
The oxygen binding curves of hemoglobin and myoglobin

are a consequence of the quaternary structure of hemoglobin
allow maximum transfer of oxygen to the tissues
both (a) and (b)
are identical

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