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Structure and Properties of Peptides

Structure and Properties of Peptides
Heme is the binding pocket of myoglobin and hemoglobin and is composed of

polar residues
hydrophobic residues
positively charged residues
negatively charged residues

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Structure and Properties of Peptides
In the β-pleated sheet

the polypeptide chain is fully extended
All of these
hydrogen bonds are formed between the peptide bonds
adjacent polypeptide chains can either be parallel or antiparallel

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

are equivalent to the (3-sheet structure
do not occur in nature
also have a cis geometry in their peptide bonds
have Y = F = 180°

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Structure and Properties of Peptides
The resonance structures that can be drawn for the peptide bond indicate that the peptide bond

is stronger than an ordinary single bond
is still not completely understood
has partial double bond character
both (a) and (b)

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Structure and Properties of Peptides
What is the proportion of glycine residues in collagenous regions?

One-third
One-tenth
One-fourth
Half

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Structure and Properties of Peptides
The peptide bond in proteins is

is planar because of steric hinderance
usually trans unless proline is the next amino acid
only found between proline residues
usually cis unless proline is the next amino acid

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