Structure and Properties of Peptides
Hydrogen bonds in a-helices are

analogous to the steps in a spiral staircase
not present at Phe residues
roughly parallel to the helix axis
more numerous than Vander Waals interactions

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Structure and Properties of Peptides
The Ramachandran Plot illustrates the fact that

the F & Y angles can assume any value in a peptide
the peptide bond is planar
the F & Y angles can assume only a single value in a protein
the F & Y angles can assume approximately three different values

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Structure and Properties of Peptides
In deoxy hemoglobin (Hb), the Fe (II) is coordinated to

four nitrogens of heme and to a water molecule
four nitrogens of heme, the proximal His, and a water molecule
two nitrogens of heme and to three water molecules
two nitrogens of heme and to three His residues in Hb

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