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Structure and Properties of Peptides

Structure and Properties of Peptides
The nature of peptide bond can be best explained as

partial double bond
Van der waals force
Hydrogen bond
truly double bond

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Pancreatic DNase
Lysozyme
Pancreatic ribonuclease
Myoglobin

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Structure and Properties of Peptides
Which of the following is an example of tertiary structure in a protein?

An a-helix
A multimeric protein
A P-pleated sheet
A globular domain

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Structure and Properties of Peptides
The oxygen binding curves of hemoglobin and myoglobin

are identical
both (a) and (b)
allow maximum transfer of oxygen to the tissues
are a consequence of the quaternary structure of hemoglobin

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Structure and Properties of Peptides
When pO2 = Kd of myoglobin, the fractional saturation (YO2) is about

0.5
0.9
1.7
0.1

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

Increase in oxygen affinity
Decrease in oxygen affinity
Increase affinity in muscle cell otherwise decrease
No effect on oxygen affinity

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