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Structure and Properties of Peptides

Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

collagen
fibrous proteins
silk protein
globular proteins

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Structure and Properties of Peptides
The peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala, was digested with cyanogen bromide (CNBr) to produce:

Val-Lys + Glu-Met-Ser + Trp-Arg-Ala
Val-Lys-Glu-Met + Ser-Trp-Arg-Ala
Val-Lys-Glu-Met-Ser-Trp + Arg-Ala
Val-Lys-Glu + Met-Ser-Trp-Arg-Ala

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Structure and Properties of Peptides
Heme is the binding pocket of myoglobin and hemoglobin and is composed of

positively charged residues
hydrophobic residues
negatively charged residues
polar residues

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Structure and Properties of Peptides
The oxygen binding curves of hemoglobin and myoglobin

are a consequence of the quaternary structure of hemoglobin
allow maximum transfer of oxygen to the tissues
both (a) and (b)
are identical

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Structure and Properties of Peptides
The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce

Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.
Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met + Ser-Trp-Arg-Ala.

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Structure and Properties of Peptides
What is the proportion of glycine residues in collagenous regions?

One-tenth
Half
One-fourth
One-third

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