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Structure and Properties of Peptides

Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

fibrous proteins
globular proteins
silk protein
collagen

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

also have a cis geometry in their peptide bonds
have Y = F = 180°
are equivalent to the (3-sheet structure
do not occur in nature

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

Increase in oxygen affinity
No effect on oxygen affinity
Decrease in oxygen affinity
Increase affinity in muscle cell otherwise decrease

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Structure and Properties of Peptides
When pO2 = Kd of myoglobin, the fractional saturation (YO2) is about

0.9
0.5
1.7
0.1

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Structure and Properties of Peptides
The resonance structures that can be drawn for the peptide bond indicate that the peptide bond

has partial double bond character
is still not completely understood
both (a) and (b)
is stronger than an ordinary single bond

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Structure and Properties of Peptides
The nature of peptide bond can be best explained as

truly double bond
Hydrogen bond
Van der waals force
partial double bond

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