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Structure and Properties of Peptides

Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

globular proteins
silk protein
collagen
fibrous proteins

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Structure and Properties of Peptides
The peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala, was digested with cyanogen bromide (CNBr) to produce:

Val-Lys-Glu + Met-Ser-Trp-Arg-Ala
Val-Lys-Glu-Met + Ser-Trp-Arg-Ala
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala
Val-Lys-Glu-Met-Ser-Trp + Arg-Ala

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Structure and Properties of Peptides
The oxygen in hemoglobin and myoglobin is bound to

the nitrogen atoms on the heme
the iron atom in the heme group
histidine residues in the protein
lysine residues in the protein

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Structure and Properties of Peptides
The nature of peptide bond can be best explained as

truly double bond
partial double bond
Van der waals force
Hydrogen bond

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Structure and Properties of Peptides
The oxygen binding curves of hemoglobin and myoglobin

both (a) and (b)
are identical
allow maximum transfer of oxygen to the tissues
are a consequence of the quaternary structure of hemoglobin

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Structure and Properties of Peptides
Which of the following is an example of tertiary structure in a protein?

A globular domain
A multimeric protein
A P-pleated sheet
An a-helix

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