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Structure and Properties of Peptides

Structure and Properties of Peptides
The heme is held in place by a bond between

the Fe3+ and cysteine
the Fe2+ and cysteine
the Fe2+ and histidine
the Fe3+ and histidine

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Lysozyme
Pancreatic ribonuclease
Myoglobin
Pancreatic DNase

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

Decrease in oxygen affinity
No effect on oxygen affinity
Increase affinity in muscle cell otherwise decrease
Increase in oxygen affinity

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Structure and Properties of Peptides
If the F and Y angles of each peptide unit in a protein are known, which of the following may also be determined?

Complete quaternary structure
Complete secondary structure
Complete tertiary structure
Thermodynamic stability

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Structure and Properties of Peptides
Disulfide bonds most often stabilize the native structure of

dimeric proteins
extracellular proteins
hydrophobic proteins
intracellular proteins

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Structure and Properties of Peptides
Hydrogen bonds in a-helices are

roughly parallel to the helix axis
analogous to the steps in a spiral staircase
not present at Phe residues
more numerous than Vander Waals interactions

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