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Structure and Properties of Peptides

Structure and Properties of Peptides
The major element of secondary structure in myoglobin and hemoglobin is

the a-helix
All of these
the reverse turn
the P-strand

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

No effect on oxygen affinity
Decrease in oxygen affinity
Increase affinity in muscle cell otherwise decrease
Increase in oxygen affinity

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

also have a cis geometry in their peptide bonds
have Y = F = 180°
are equivalent to the (3-sheet structure
do not occur in nature

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Structure and Properties of Peptides
Heme is the binding pocket of myoglobin and hemoglobin and is composed of

polar residues
negatively charged residues
hydrophobic residues
positively charged residues

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Structure and Properties of Peptides
If the F and Y angles of each peptide unit in a protein are known, which of the following may also be determined?

Complete quaternary structure
Complete tertiary structure
Thermodynamic stability
Complete secondary structure

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Structure and Properties of Peptides
Which of the three subunits of the G proteins binds GDP and GTP?

Gamma
Alpha
Delta
Beta

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