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Structure and Properties of Peptides

Structure and Properties of Peptides
The major element of secondary structure in myoglobin and hemoglobin is

the reverse turn
the a-helix
the P-strand
All of these

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Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

fibrous proteins
globular proteins
silk protein
collagen

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Structure and Properties of Peptides
Hydrogen bonds in a-helices are

not present at Phe residues
roughly parallel to the helix axis
analogous to the steps in a spiral staircase
more numerous than Vander Waals interactions

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Structure and Properties of Peptides
When pO2 = Kd of myoglobin, the fractional saturation (YO2) is about

0.1
0.5
0.9
1.7

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Myoglobin
Lysozyme
Pancreatic ribonuclease
Pancreatic DNase

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Structure and Properties of Peptides
The oxygen binding curves of hemoglobin and myoglobin

allow maximum transfer of oxygen to the tissues
are identical
both (a) and (b)
are a consequence of the quaternary structure of hemoglobin

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