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Structure and Properties of Peptides

Structure and Properties of Peptides
Disulfide bonds most often stabilize the native structure of

extracellular proteins
intracellular proteins
hydrophobic proteins
dimeric proteins

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Structure and Properties of Peptides
The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce

Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met + Ser-Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.

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Structure and Properties of Peptides
Which of the three subunits of the G proteins binds GDP and GTP?

Alpha
Delta
Gamma
Beta

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Pancreatic ribonuclease
Pancreatic DNase
Lysozyme
Myoglobin

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

Decrease in oxygen affinity
No effect on oxygen affinity
Increase in oxygen affinity
Increase affinity in muscle cell otherwise decrease

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Structure and Properties of Peptides
Hydrogen bonds in a-helices are

not present at Phe residues
more numerous than Vander Waals interactions
roughly parallel to the helix axis
analogous to the steps in a spiral staircase

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