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Water, pH and Macromolecules

Water, pH and Macromolecules
Which of the following acid/base pairs act as natural buffers in living systems?

All of these
Histidine+/histidine
H2PO4-/HPO42-
H2CO3/HCO3-

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Water, pH and Macromolecules
A compound that is capable of forming hydrogen bonds with water

contains at least some polar covalent bonds
is probably held together by noncovalent bonds
does not dissolve well in water
should act as a good buffer for acids and bases

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Water, pH and Macromolecules
A Bronsted acid becomes __________ upon losing a proton.

a hydronium ion
highly reactive
its conjugate acid
its conjugate base

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Water, pH and Macromolecules
Weak acids generally have pKa

values less than 1
that cannot be used to buffer
been seldom found in living systems
pKa values greater than 2

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Water, pH and Macromolecules
The pH of a solution is determined by

relative concentration of acids and bases
dielectric constant of the medium
concentration of salt
environmental effect

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Water, pH and Macromolecules
The elements oxygen, nitrogen, and carbon

are common elements in the molecules that make up living organisms
All of these
can all form covalent bonds with other elements
contain protons and neutrons in their atomic nuclei

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