Water, pH and Macromolecules
Weak acids generally have pKa

been seldom found in living systems
that cannot be used to buffer
pKa values greater than 2
values less than 1

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Water, pH and Macromolecules
Buffer solutions

tend to maintain a relatively constant pH.
will always have a pH of 7
cause a decrease in pH when acids are added to them.
are rarely found in living systems

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