Water, pH and Macromolecules
Weak acids generally have pKa

been seldom found in living systems
pKa values greater than 2
that cannot be used to buffer
values less than 1

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Water, pH and Macromolecules
Buffer solutions

will always have a pH of 7
are rarely found in living systems
tend to maintain a relatively constant pH.
cause a decrease in pH when acids are added to them.

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