Water, pH and Macromolecules
Weak acids generally have pKa

been seldom found in living systems
values less than 1
pKa values greater than 2
that cannot be used to buffer

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Water, pH and Macromolecules
The main difference between an acid and a base is that

bases donate hydrogen ions in water while acids accept hydrogen ions
bases are polar molecules and acids are not
acids donate hydrogen ions in water while bases accept hydrogen ions
acids are polar molecules and bases are not

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