Water, pH and Macromolecules
Weak acids generally have pKa

that cannot be used to buffer
pKa values greater than 2
been seldom found in living systems
values less than 1

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Water, pH and Macromolecules
Salt dissolves well in water as water molecules

form hydrogen bonds with the positively and negatively charged ions
make nonpolar covalent bonds with the positively charged ions only
share electrons with the ions to make polar covalent bonds
surround the ions because of their charge but do not form hydrogen bonds

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