Recombinant DNA Technology
Under which of the following conditions would population gene frequencies remain the same?

Selection for homozygotes
Active migration between groups
Random mating
Small population size

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Recombinant DNA Technology
Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

short sequences that will hybridize only to a specific base sequence
copies of the gene with an altered sequence so that a restriction site is inserted
PCR-amplified variable numbers of tandem repeats (VNTRs)
mutagenized copies of a gene

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Recombinant DNA Technology
Knockout mice are created by

transfecting embryonic stem cells with an altered gene sequence
creating a chimera by fusing cells from two different cell lines
mutagenizing a mouse and selecting for mutant offspring
infecting the mouse with a retrovirus

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Recombinant DNA Technology
A human cDNA library

contains DNA for specific human proteins
cannot be used to obtain human genes because it would be radioactive
contains DNA for virtually all of the human proteins in vectors
None of these

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