DNA Structure and Replication
The RNA primers used to initiate replication in E. coli

result in Okazaki fragments on leading strand
are removed by Pol I
are removed by helicase + ATP
are joined together by DNA ligase

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DNA Structure and Replication
The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?

AZT (zidovudine) is too expensive to be taken in effective doses
It lacks a proofreading exonuclease
The RNase H domain of p66 causes error prone synthesis
It has low affinity for the correct dNTP's

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