DNA Structure and Replication
DNA gyrase in E. coli

is required only at the oriC site
can be inhibited with antibiotics
performs the same function as helicase in eukaryotes
adds positive supercoils to chromosomal DNA

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DNA Structure and Replication
In a typical electrophoresis experiment, larger fragments of DNA move more

slowly, so they appear nearer the top of a gel photograph
slowly, so they appear nearer the bottom of a gel photograph
quickly, so they appear nearer the bottom of a gel photograph
quickly, so they appear nearer the top of a gel photograph

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