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Disease Associated with Immune System

Disease Associated with Immune System
Specific translocations are associated with

some leukemias
pancreatic cancer
breast cancer
colon cancer

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Disease Associated with Immune System
A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

Leu or Ileu
His or Pro
Tyr or Phe
Ser or Thr

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Disease Associated with Immune System
Retinoblastoma is due to a mutation in a

tumor supressor
viral gene
cyclin
kinase

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Disease Associated with Immune System
Combined cellular and humoral immune deficiencies result from lack of all of the following except

a thymus
HIV infection of CD4+ T cells
transporter of antigen peptides (TAP)
class II MHC

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Disease Associated with Immune System
An example of an immunodeficiency disorder is

rheumatic fever
systemic lupus erythematosus
AIDS
thyroiditis

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Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

CD8 T cell-mediated cytotoxicity
IgG synthesis
macrophage activation to vesicular pathogens
alternative complement activation.

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