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Disease Associated with Immune System

Disease Associated with Immune System
Specific translocations are associated with

breast cancer
some leukemias
pancreatic cancer
colon cancer

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Disease Associated with Immune System
An autoimmune disease is

Lupus
AIDS
Mumps
Measles

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Disease Associated with Immune System
An example of an immunodeficiency disorder is

systemic lupus erythematosus
rheumatic fever
thyroiditis
AIDS

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Disease Associated with Immune System
Combined cellular and humoral immune deficiencies result from lack of all of the following except

class II MHC
HIV infection of CD4+ T cells
transporter of antigen peptides (TAP)
a thymus

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Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

macrophage activation to vesicular pathogens
alternative complement activation.
IgG synthesis
CD8 T cell-mediated cytotoxicity

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Disease Associated with Immune System
Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 12-24 months of age
in utero (before birth)
at 0-3 months of age
at 3-12 months of age

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