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Disease Associated with Immune System

Disease Associated with Immune System
Specific translocations are associated with

breast cancer
colon cancer
pancreatic cancer
some leukemias

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Disease Associated with Immune System
Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 12-24 months of age
in utero (before birth)
at 0-3 months of age
at 3-12 months of age

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Disease Associated with Immune System
A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

Leu or Ileu
Ser or Thr
His or Pro
Tyr or Phe

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Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

macrophage activation to vesicular pathogens
IgG synthesis
CD8 T cell-mediated cytotoxicity
alternative complement activation.

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Disease Associated with Immune System
An example of an immunodeficiency disorder is

rheumatic fever
AIDS
thyroiditis
systemic lupus erythematosus

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Disease Associated with Immune System
Combined cellular and humoral immune deficiencies result from lack of all of the following except

class II MHC
transporter of antigen peptides (TAP)
a thymus
HIV infection of CD4+ T cells

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