Disease Associated with Immune System
The primary reason for AIDS, a deadly disease is that it

destroys key components of the body's internal defense system
is caused by a bacterium
is caused by a virus
causes a breakdown of the body's inflammatory response

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Disease Associated with Immune System
X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

failure of B cells to provide co-stimulation for Th2 activation
activation of B cells by T-independent antigens
failure of Th2 cells to provide co-stimulation for B cell proliferation
failure of Th2 cells to provide co-stimulation for B cell isotype switching

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