Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

macrophage activation to vesicular pathogens
alternative complement activation.
CD8 T cell-mediated cytotoxicity
IgG synthesis

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Disease Associated with Immune System
Difficulties with somatic gene therapy arise from all of the following except

inserting a gene so that it will function properly
transducing genetic material into stem cells
GVHD caused by mature T cells in the transplanted cells
limited life span of more mature hematopoietic cells

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