Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

alternative complement activation.
IgG synthesis
macrophage activation to vesicular pathogens
CD8 T cell-mediated cytotoxicity

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Disease Associated with Immune System
To treat HIV infections using drugs, the major problem is that

the drugs are rapidly degraded
the drugs that are good inhibitors cannot by synthesized
the virus particles with altered (mutant) proteases arise
the drugs interfere with normal digestion

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