Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

IgG synthesis
alternative complement activation.
CD8 T cell-mediated cytotoxicity
macrophage activation to vesicular pathogens

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Disease Associated with Immune System
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

macrophage intracellular killing of bacteria
infected cell processing of virus peptides
dendritic cell activation to become a mature APC
CTL killing of viruses

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