Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

IgG synthesis
alternative complement activation.
CD8 T cell-mediated cytotoxicity
macrophage activation to vesicular pathogens

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Disease Associated with Immune System
To treat HIV infections using drugs, the major problem is that

the drugs interfere with normal digestion
the virus particles with altered (mutant) proteases arise
the drugs are rapidly degraded
the drugs that are good inhibitors cannot by synthesized

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