Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

CD8 T cell-mediated cytotoxicity
macrophage activation to vesicular pathogens
alternative complement activation.
IgG synthesis

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Disease Associated with Immune System
Difficulties with somatic gene therapy arise from all of the following except

transducing genetic material into stem cells
GVHD caused by mature T cells in the transplanted cells
inserting a gene so that it will function properly
limited life span of more mature hematopoietic cells

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