Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

IgG synthesis
CD8 T cell-mediated cytotoxicity
alternative complement activation.
macrophage activation to vesicular pathogens

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Disease Associated with Immune System
Difficulties with somatic gene therapy arise from all of the following except

GVHD caused by mature T cells in the transplanted cells
transducing genetic material into stem cells
inserting a gene so that it will function properly
limited life span of more mature hematopoietic cells

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