Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

macrophage activation to vesicular pathogens
IgG synthesis
CD8 T cell-mediated cytotoxicity
alternative complement activation.

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Disease Associated with Immune System
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

macrophage intracellular killing of bacteria
dendritic cell activation to become a mature APC
infected cell processing of virus peptides
CTL killing of viruses

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Disease Associated with Immune System
To treat HIV infections using drugs, the major problem is that

the drugs interfere with normal digestion
the drugs are rapidly degraded
the drugs that are good inhibitors cannot by synthesized
the virus particles with altered (mutant) proteases arise

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Disease Associated with Immune System
Difficulties with somatic gene therapy arise from all of the following except

inserting a gene so that it will function properly
transducing genetic material into stem cells
limited life span of more mature hematopoietic cells
GVHD caused by mature T cells in the transplanted cells

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