Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

IgG synthesis
alternative complement activation.
macrophage activation to vesicular pathogens
CD8 T cell-mediated cytotoxicity

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Disease Associated with Immune System
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

macrophage intracellular killing of bacteria
dendritic cell activation to become a mature APC
infected cell processing of virus peptides
CTL killing of viruses

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Disease Associated with Immune System
Bone marrow given to an infant with SCID must

contain mature T cells that can begin making immune responses immediately
be irradiated to eliminate GVHD
come from a donor that shares some MHC alleles with the recipient
come from one of the child's parents

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