Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

CD8 T cell-mediated cytotoxicity
alternative complement activation.
IgG synthesis
macrophage activation to vesicular pathogens

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Disease Associated with Immune System
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

CTL killing of viruses
infected cell processing of virus peptides
macrophage intracellular killing of bacteria
dendritic cell activation to become a mature APC

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