Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

macrophage activation to vesicular pathogens
alternative complement activation.
IgG synthesis
CD8 T cell-mediated cytotoxicity

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Disease Associated with Immune System
Bone marrow given to an infant with SCID must

contain mature T cells that can begin making immune responses immediately
come from a donor that shares some MHC alleles with the recipient
come from one of the child's parents
be irradiated to eliminate GVHD

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Disease Associated with Immune System
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

infected cell processing of virus peptides
macrophage intracellular killing of bacteria
CTL killing of viruses
dendritic cell activation to become a mature APC

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Disease Associated with Immune System
To treat HIV infections using drugs, the major problem is that

the drugs that are good inhibitors cannot by synthesized
the drugs interfere with normal digestion
the drugs are rapidly degraded
the virus particles with altered (mutant) proteases arise

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