Disease Associated with Immune System
Combined cellular and humoral immune deficiencies result from lack of all of the following except

a thymus
HIV infection of CD4+ T cells
transporter of antigen peptides (TAP)
class II MHC

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Disease Associated with Immune System
Bone marrow given to an infant with SCID must

be irradiated to eliminate GVHD
contain mature T cells that can begin making immune responses immediately
come from one of the child's parents
come from a donor that shares some MHC alleles with the recipient

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Disease Associated with Immune System
To treat HIV infections using drugs, the major problem is that

the virus particles with altered (mutant) proteases arise
the drugs interfere with normal digestion
the drugs that are good inhibitors cannot by synthesized
the drugs are rapidly degraded

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