Disease Associated with Immune System
Combined cellular and humoral immune deficiencies result from lack of all of the following except

a thymus
class II MHC
transporter of antigen peptides (TAP)
HIV infection of CD4+ T cells

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Disease Associated with Immune System
To treat HIV infections using drugs, the major problem is that

the drugs are rapidly degraded
the drugs interfere with normal digestion
the virus particles with altered (mutant) proteases arise
the drugs that are good inhibitors cannot by synthesized

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