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Disease Associated with Immune System

Disease Associated with Immune System
Retinoblastoma is due to a mutation in a

tumor supressor
kinase
cyclin
viral gene

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Disease Associated with Immune System
A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

Tyr or Phe
Ser or Thr
His or Pro
Leu or Ileu

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Disease Associated with Immune System
An autoimmune disease is

Mumps
Lupus
Measles
AIDS

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Disease Associated with Immune System
An example of an immunodeficiency disorder is

AIDS
systemic lupus erythematosus
thyroiditis
rheumatic fever

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Disease Associated with Immune System
Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 0-3 months of age
in utero (before birth)
at 3-12 months of age
at 12-24 months of age

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Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

alternative complement activation.
IgG synthesis
CD8 T cell-mediated cytotoxicity
macrophage activation to vesicular pathogens

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