Disease Associated with Immune System
DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a

knock-out mouse for RAG-1 and RAG-2
recombinant mouse for CD3
nude mouse
knock-out mouse for a thymus

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Disease Associated with Immune System
Difficulties with somatic gene therapy arise from all of the following except

limited life span of more mature hematopoietic cells
GVHD caused by mature T cells in the transplanted cells
transducing genetic material into stem cells
inserting a gene so that it will function properly

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