Disease Associated with Immune System
Bone marrow given to an infant with SCID must

be irradiated to eliminate GVHD
come from a donor that shares some MHC alleles with the recipient
come from one of the child's parents
contain mature T cells that can begin making immune responses immediately

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Disease Associated with Immune System
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

infected cell processing of virus peptides
dendritic cell activation to become a mature APC
macrophage intracellular killing of bacteria
CTL killing of viruses

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