Process Equipment and Plant Design
Shortest distance between two tubes is

None of these
Called tube clearance
Called tube pitch
More in case of triangular pitch as compared to square pitch of tube layout

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Process Equipment and Plant Design
High pressure fluid in a shell and tube heat exchanger should preferably be routed through the

Tubes to avoid the expansion of high pressure shell construction
Shell side, if the flow is counter-current and tube side if the flow is co-current
Shell side for smaller total pressure drop
Shell side for large overall heat transfer co-efficient

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