Recombinant DNA Technology
In order to insert a foreign gene into a plasmid, both must __________

be cut by the same restriction enzyme
originate from the same type of cell
have identical DNA sequences
be of the same length

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Recombinant DNA Technology
Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

short sequences that will hybridize only to a specific base sequence
mutagenized copies of a gene
copies of the gene with an altered sequence so that a restriction site is inserted
PCR-amplified variable numbers of tandem repeats (VNTRs)

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