Recombinant DNA Technology
In gel electrophoresis, DNA molecules migrate from __________ to __________ ends of the gel.

basic ... acidic
negative ... positive
positive to negative
long ... short

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Recombinant DNA Technology
Knockout mice are created by

mutagenizing a mouse and selecting for mutant offspring
transfecting embryonic stem cells with an altered gene sequence
infecting the mouse with a retrovirus
creating a chimera by fusing cells from two different cell lines

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Recombinant DNA Technology
Which of the following is correct in terms of determination of location of genetic traits?

Restriction sites allow DNAs to be digested
Protein-coding genes are always associated with a restriction pattern
Known protein coding sequences are too far apart to allow linkage determination for most new genes
None of these

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