Cloning Vectors
Cos site of the cosmids

both (a) and (b)
helps whole genome in circularization and ligation
consists of 12 bases
contains cleavage site

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Cloning Vectors
Cosmids lack

cleavage site for the insertion of foreign DNA
genes coding for viral proteins
marker genes coding for replication
origin of replication

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Cloning Vectors
Charon vectors are different from EMBL vectors because

they have more extensive range of restriction targets with in their polylinkers.
physical separation of lambda arm from central fragment is not required
physical separation of lambda arm from central fragment is required
both (a) and (b)

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