Cloning Vectors
Cos site of the cosmids

both (a) and (b)
consists of 12 bases
helps whole genome in circularization and ligation
contains cleavage site

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Cloning Vectors
Charon vectors are different from EMBL vectors because

they have more extensive range of restriction targets with in their polylinkers.
physical separation of lambda arm from central fragment is required
both (a) and (b)
physical separation of lambda arm from central fragment is not required

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