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Antibiotics

Antibiotics
Chlorotetracyclin is soluble in

water
ether
all of these
organic solvents

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

antibiotic yields are generally higher when cells enter the stationary phase
the precursors are often toxic to the cells
All of these
antibiotic yields are generally higher when cell growth slows

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Antibiotics
High yield of chlorotetracyclin requires

no aeration
continuous aeration
controlled aeration
aeration which does not affect the yield

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Antibiotics
pH of the fermentation medium for chlorotetracyclins is

7-8
5-6
6-7
8-9

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Antibiotics
Media used for the production of chlorotetracyclin consists of

corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
corn steep liquor, CaCO3 and (NH4)2SO4
sugar, CaCO3 and (NH4)2SO4
sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl

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Antibiotics
Penicillin is recovered after fermentation as

sodium penicillin
potassium penicillin
penicillin only
calcium penicillin

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