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Antibiotics

Antibiotics
At acidic pH, penicillin remains in

both (a) and (b)
aqueous phase
precipitates
solvent phase

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Antibiotics
The yield of the antibiotic depends upon

composition of the medium
pH of the medium
all of these
age of the inoculum

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Antibiotics
High yield of chlorotetracyclin requires

no aeration
aeration which does not affect the yield
continuous aeration
controlled aeration

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Antibiotics
Media used for the production of chlorotetracyclin consists of

sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
corn steep liquor, CaCO3 and (NH4)2SO4
sugar, CaCO3 and (NH4)2SO4
corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

the precursors are often toxic to the cells
antibiotic yields are generally higher when cells enter the stationary phase
antibiotic yields are generally higher when cell growth slows
All of these

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Antibiotics
Which of the following changes occur during first phase of growth of Penicillium chrysogenum?

Growth of mycelia occurs
Lactic acid present in the corn steep liquor is utilized at the maximum rate
Ammonia is liberated in the medium
All of these

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