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Antibiotics

Antibiotics
pH of the fermentation medium for chlorotetracyclins is

8-9
5-6
7-8
6-7

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Antibiotics
Fermentation medium for oxytetracyclin (terramycin) consist of

CSL,(NH4)2 SO4, ammonium chloride and CaCO3
CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
CSL, (NH4)2 SO4, sodium chloride and CaCO3
CSL, starch,(NH4)2 SO4, ammonium chloride and CaCO3

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Antibiotics
Which of the following event occurs during second phase of growth of P. chrysogenum?

pH increase
Synthesis of penicillin is high
Both (a) and (b)
Mycelial mass increases

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

antibiotic yields are generally higher when cells enter the stationary phase
the precursors are often toxic to the cells
antibiotic yields are generally higher when cell growth slows
All of these

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Antibiotics
Chlorotetracyclin is soluble in

all of these
organic solvents
ether
water

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Antibiotics
Which of the following organism(s) produce(s) tetracycline?

All of these
Steptomyces ramosus
Steptomyces aureofaciens
Nocardia sulphurea

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