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Antibiotics

Antibiotics
pH of the fermentation medium for chlorotetracyclins is

7-8
8-9
6-7
5-6

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

All of these
antibiotic yields are generally higher when cells enter the stationary phase
antibiotic yields are generally higher when cell growth slows
the precursors are often toxic to the cells

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Antibiotics
Which of the following precursor is added in the medium to get penicillin G?

Ammonium sulphate
Ammonium chloride
Phenyl carbamic acid
Phenyl acetic acid

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Antibiotics
At normal pH, penicillin remains in

both (a) and (b)
precipitates
aqueous phase
solvent phase

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Antibiotics
Which of the following changes occur during first phase of growth of Penicillium chrysogenum?

Ammonia is liberated in the medium
All of these
Lactic acid present in the corn steep liquor is utilized at the maximum rate
Growth of mycelia occurs

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Antibiotics
Chlorotetracyclin is soluble in

ether
organic solvents
water
all of these

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