Water, pH and Macromolecules
The main difference between an acid and a base is that

acids donate hydrogen ions in water while bases accept hydrogen ions
bases are polar molecules and acids are not
bases donate hydrogen ions in water while acids accept hydrogen ions
acids are polar molecules and bases are not

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Water, pH and Macromolecules
Hydrogen bonds and hydrophilic interactions are types of

strong chemical bonds that hold together the atoms within a molecule
weak chemical bonds that link together separate molecules
weak chemical bonds that hold together the atoms within a molecule
strong chemical bonds that link together separate molecules

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