Monoclonal Antibodies The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as combination of EB Vand hybridoma techniques all of these hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes transformation of antigen specific B lymphocytes (EBV) combination of EB Vand hybridoma techniques all of these hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes transformation of antigen specific B lymphocytes (EBV) ANSWER DOWNLOAD EXAMIANS APP
Monoclonal Antibodies The antigen-specific lymphocytes can be immortalized by which of the following method? All of these Transformation following infection by Epstein-Barr virus (EB V) Transfection with tumor derived DNA Hybridization with a suitable lymphoid tumor cell All of these Transformation following infection by Epstein-Barr virus (EB V) Transfection with tumor derived DNA Hybridization with a suitable lymphoid tumor cell ANSWER DOWNLOAD EXAMIANS APP
Monoclonal Antibodies Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the All of these presence of HAMA response absence of human immune response against murine proteins (HAMA) response poor recognition of immunoglobulin, Ig constant regions All of these presence of HAMA response absence of human immune response against murine proteins (HAMA) response poor recognition of immunoglobulin, Ig constant regions ANSWER DOWNLOAD EXAMIANS APP
Monoclonal Antibodies The hybrid cells can be propagated none of these as ascites in peritoneal cavity of mice in tissue culture both (a) and (b) none of these as ascites in peritoneal cavity of mice in tissue culture both (a) and (b) ANSWER DOWNLOAD EXAMIANS APP
Monoclonal Antibodies The EBV-hybridoma technique facilitates the proliferation of antigen specific B cells immortalizes the donor Bcells gives much higher hybridization frequencies All of these facilitates the proliferation of antigen specific B cells immortalizes the donor Bcells gives much higher hybridization frequencies All of these ANSWER DOWNLOAD EXAMIANS APP
Monoclonal Antibodies The Ig locus is about 1/4th of all hybridomas 2/3rd of all hybridomas l/3rd of all hybridomas l/2nd of all hybridomas 1/4th of all hybridomas 2/3rd of all hybridomas l/3rd of all hybridomas l/2nd of all hybridomas ANSWER DOWNLOAD EXAMIANS APP