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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Quinolones are

broad-spectrum
penicillin derivatives
bacteriostatic
antimetabolites

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Antimicrobial Chemotherapeutic Agents
Which of the following protein synthesis mechanisms may be affected by particular drugs?

Aminoacyl-tRNA binding
mRNA translocation
All of these
Peptide bond formation

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Antimicrobial Chemotherapeutic Agents
Novobiocin can be used against

gram +ve Staphylococci
all of these
Haemophilus
gram -ve Meningococci & Gonococci

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Antimicrobial Chemotherapeutic Agents
Which of the following group is not the carbohydrate containing antibiotic?

Everninomycin & Nogirimycin
Vancomycin & Moenomycin
Streptomycin & Streptothricin
Erythromycin & candicidin

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Antimicrobial Chemotherapeutic Agents
Which of the following may cause resistance to penicillin?

All of these
Impermeability of cell envelope
Production of β-lactamases by bacteria
Alteration or lack of penicillin-binding proteins

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

must be transported into the cytoplasm in order to act
inhibit the cross-linking of peptidoglycan
bind to and inactivate a bacterial protein
are inactivated by β-lactamase

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