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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Quinolones are

broad-spectrum
antimetabolites
bacteriostatic
penicillin derivatives

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Antimicrobial Chemotherapeutic Agents
Nystatin is a drug used for treatment of diseases caused by

yeast
protozoan
gram positive bacterium
gram negative bacterium

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Antimicrobial Chemotherapeutic Agents
Vancomycin inhibits peptidoglycan synthesis by binding

D-alanyl - D-alanine synthetase
D-alanyl - D-alanine
alanine racemase
amidase

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Antimicrobial Chemotherapeutic Agents
A broad-spectrum antibiotic such as chloramphenicol is one that

kills all microorganisms
kills numerous types of microbes
kills all bacteria
kills both Gram positive and Gram negative bacteria

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Antimicrobial Chemotherapeutic Agents
The nitrofurans differ from the antibiotics in that they

occur naturally
all of these
do not occur naturally
are antimicrobial drugs

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

bind to and inactivate a bacterial protein
must be transported into the cytoplasm in order to act
inhibit the cross-linking of peptidoglycan
are inactivated by β-lactamase

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