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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The mode of action of polymyxin is to

inhibit DNA synthesis
inhibit protein synthesis
inhibit folic acid synthesis
injury to the plasma membrane

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

inhibit the cross-linking of peptidoglycan
are inactivated by β-lactamase
bind to and inactivate a bacterial protein
must be transported into the cytoplasm in order to act

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Antimicrobial Chemotherapeutic Agents
Chelate forming peptide antibiotic are/is

both (a) and (b)
vancomycin
sideromycins
bleomycins

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Antimicrobial Chemotherapeutic Agents
Which of the following may cause resistance to penicillin?

Alteration or lack of penicillin-binding proteins
Impermeability of cell envelope
All of these
Production of β-lactamases by bacteria

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Antimicrobial Chemotherapeutic Agents
Most antibiotics are isolated from

soil microorganisms
plants
viruses
aquatic microorganisms

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Antimicrobial Chemotherapeutic Agents
Which of the following group is not the carbohydrate containing antibiotic?

Everninomycin & Nogirimycin
Erythromycin & candicidin
Streptomycin & Streptothricin
Vancomycin & Moenomycin

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