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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Which of the following antibiotics can't be used for treatment of infections with β-lactamase-producing Staphylococcus aureus?

Ampicillin/sulbactam
Vancomycin
Piperacillin
Cephalothin

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Antimicrobial Chemotherapeutic Agents
The most selective antibiotics are those that interfere with the synthesis of

bacterial DNA
bacterial RNA
bacterial plasma membrane
bacterial cell walls

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Antimicrobial Chemotherapeutic Agents
Which of the following is used only in life-threatening situations when no other drug is adequate?

Tetracycline
Streptomycin
Penicillin
Chloramphenicol

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Antimicrobial Chemotherapeutic Agents
Amphotericin B and polymyxin interfere with

cell membrane function
protein synthesis
cell wall synthesis
DNA function

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Antimicrobial Chemotherapeutic Agents
Novobiocin can be used against

all of these
Haemophilus
gram -ve Meningococci & Gonococci
gram +ve Staphylococci

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Antimicrobial Chemotherapeutic Agents
Who developed the concept of specific toxicity?

Ehrlich
Fleming
Pasteur
Watson

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