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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Which antibiotic has a beta-lactam ring?

Tetracycline
Streptomycin
Penicillin
Cephalosporin

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Antimicrobial Chemotherapeutic Agents
Most antibiotics are isolated from

plants
aquatic microorganisms
viruses
soil microorganisms

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Antimicrobial Chemotherapeutic Agents
Which of the following protein synthesis mechanisms may be affected by particular drugs?

Peptide bond formation
Aminoacyl-tRNA binding
mRNA translocation
All of these

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Antimicrobial Chemotherapeutic Agents
Vancomycin inhibits peptidoglycan synthesis by binding

D-alanyl - D-alanine
amidase
D-alanyl - D-alanine synthetase
alanine racemase

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Antimicrobial Chemotherapeutic Agents
Who developed the concept of specific toxicity?

Pasteur
Fleming
Ehrlich
Watson

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

are inactivated by β-lactamase
inhibit the cross-linking of peptidoglycan
must be transported into the cytoplasm in order to act
bind to and inactivate a bacterial protein

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