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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The antibiotics which affords a broad spectrum of antimicrobial coverage against aerobic and anaerobic bacteria, rickettsiae, chlamydiae, and mycoplasmas is

gentamicin
metronidazole
tetracycline
vancomycin

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Antimicrobial Chemotherapeutic Agents
Which of the following may cause resistance to penicillin?

Alteration or lack of penicillin-binding proteins
All of these
Impermeability of cell envelope
Production of β-lactamases by bacteria

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Antimicrobial Chemotherapeutic Agents
Polyene antibiotics are

small ring structures
β-lactam - thiazolidine ring
any of these
large ring structures

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Antimicrobial Chemotherapeutic Agents
Most antibiotics are isolated from

aquatic microorganisms
viruses
soil microorganisms
plants

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Antimicrobial Chemotherapeutic Agents
The mode of action of polymyxin is to

inhibit folic acid synthesis
inhibit DNA synthesis
injury to the plasma membrane
inhibit protein synthesis

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Antimicrobial Chemotherapeutic Agents
The antibiotics not having good activity against Enterobacteriaceae is

ciprofloxacin
cefoxitin
clindamycin
trimethoprim-sulphamethoxazole

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