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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Vancomycin inhibits peptidoglycan synthesis by binding

D-alanyl - D-alanine synthetase
D-alanyl - D-alanine
amidase
alanine racemase

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Antimicrobial Chemotherapeutic Agents
Which of the following may cause resistance to penicillin?

Production of β-lactamases by bacteria
Impermeability of cell envelope
All of these
Alteration or lack of penicillin-binding proteins

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Antimicrobial Chemotherapeutic Agents
Bacterial cells susceptible to penicillium can be protected from destruction if the medium in which they are exposed is of

moderate osmotic pressure
high osmotic pressure
low osmotic pressure
high surface tension

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Antimicrobial Chemotherapeutic Agents
Chemotherapeutic agents must

be able to come in contact with the parasite by penetrating the cells
prevent/destroy the activity of a parasite
All of these
leave unaltered the host's natural defense mechanisms

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Antimicrobial Chemotherapeutic Agents
Which of the following drugs involves modification of the drug by enzymatic modification or degradation of its active element to alter its/their resistance?

Aminoglyosides
All of these
Choloramphenicol
Pencillins

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

are inactivated by β-lactamase
must be transported into the cytoplasm in order to act
inhibit the cross-linking of peptidoglycan
bind to and inactivate a bacterial protein

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