Gel Electrophoresis
In an SDS-PAGE

smaller proteins migrate more rapidly through the gel
proteins are denatured by the SDS
All of these
proteins have the same charge-to-mass ratio

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Gel Electrophoresis
Electrophoresis of histones and myoglobin under non-denaturing conditions (pH = 7.0) results in

both proteins migrate to the cathode
histones migrate to the cathode and myoglobin migrates to the anode
histones migrate to the anode and myoglobin migrates to the cathode
both proteins migrate to the anode

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