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Antibiotics

Antibiotics
At normal pH, penicillin remains in

both (a) and (b)
precipitates
aqueous phase
solvent phase

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Antibiotics
Which of the following event occurs during second phase of growth of P. chrysogenum?

Mycelial mass increases
Synthesis of penicillin is high
pH increase
Both (a) and (b)

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

antibiotic yields are generally higher when cell growth slows
the precursors are often toxic to the cells
antibiotic yields are generally higher when cells enter the stationary phase
All of these

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Antibiotics
Which of the following event occurs during third phase of growth of P chrysogenum?

All of these
Concentration of antibiotic increases in the medium
Autolysis of the medium starts
Slight rise in pH due to liberation of ammonia

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Antibiotics
High yield of chlorotetracyclin requires

continuous aeration
aeration which does not affect the yield
controlled aeration
no aeration

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Antibiotics
Fermentation medium for oxytetracyclin (terramycin) consist of

CSL, starch,(NH4)2 SO4, ammonium chloride and CaCO3
CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
CSL, (NH4)2 SO4, sodium chloride and CaCO3
CSL,(NH4)2 SO4, ammonium chloride and CaCO3

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