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Antibiotics

Antibiotics
At normal pH, penicillin remains in

solvent phase
aqueous phase
precipitates
both (a) and (b)

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Antibiotics
Media used for the production of chlorotetracyclin consists of

sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
sugar, CaCO3 and (NH4)2SO4
corn steep liquor, CaCO3 and (NH4)2SO4
corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

All of these
antibiotic yields are generally higher when cells enter the stationary phase
antibiotic yields are generally higher when cell growth slows
the precursors are often toxic to the cells

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Antibiotics
The yield of the antibiotic depends upon

age of the inoculum
composition of the medium
pH of the medium
all of these

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Antibiotics
Fermentation medium for oxytetracyclin (terramycin) consist of

CSL, starch,(NH4)2 SO4, ammonium chloride and CaCO3
CSL,(NH4)2 SO4, ammonium chloride and CaCO3
CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
CSL, (NH4)2 SO4, sodium chloride and CaCO3

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Antibiotics
Streptomycin is produced by

S. griseoflavus
S. aerofaciens
S. griseus
S. ramosus

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