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Antibiotics

Antibiotics
At normal pH, penicillin remains in

both (a) and (b)
solvent phase
precipitates
aqueous phase

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

antibiotic yields are generally higher when cell growth slows
All of these
the precursors are often toxic to the cells
antibiotic yields are generally higher when cells enter the stationary phase

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Antibiotics
Vegetable oil, (corn oil or soybean oil) added in the fermentation medium for penicillin, act as

antifoam agent
carbon source
source of nutrients
both (a) and (c)

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Antibiotics
Which of the following event occurs during second phase of growth of P. chrysogenum?

Both (a) and (b)
Mycelial mass increases
Synthesis of penicillin is high
pH increase

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Antibiotics
Media used for the production of chlorotetracyclin consists of

sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
corn steep liquor, CaCO3 and (NH4)2SO4
corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
sugar, CaCO3 and (NH4)2SO4

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Antibiotics
pH of the fermentation medium for chlorotetracyclins is

8-9
7-8
5-6
6-7

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