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Antibiotics

Antibiotics
At normal pH, penicillin remains in

aqueous phase
solvent phase
both (a) and (b)
precipitates

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Antibiotics
Chlorotetracyclin is soluble in

all of these
organic solvents
water
ether

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Antibiotics
Streptomycin is produced by

S. griseoflavus
S. griseus
S. ramosus
S. aerofaciens

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Antibiotics
At acidic pH, penicillin remains in

aqueous phase
solvent phase
precipitates
both (a) and (b)

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Antibiotics
pH of the fermentation medium for chlorotetracyclins is

5-6
7-8
6-7
8-9

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

antibiotic yields are generally higher when cell growth slows
All of these
the precursors are often toxic to the cells
antibiotic yields are generally higher when cells enter the stationary phase

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