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Antibiotics

Antibiotics
At normal pH, penicillin remains in

precipitates
aqueous phase
solvent phase
both (a) and (b)

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Antibiotics
pH of the fermentation medium for chlorotetracyclins is

5-6
8-9
6-7
7-8

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

the precursors are often toxic to the cells
All of these
antibiotic yields are generally higher when cells enter the stationary phase
antibiotic yields are generally higher when cell growth slows

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Antibiotics
Media used for the production of chlorotetracyclin consists of

corn steep liquor, CaCO3 and (NH4)2SO4
sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
sugar, CaCO3 and (NH4)2SO4
corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl

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Antibiotics
Which of the following event occurs during second phase of growth of P. chrysogenum?

Synthesis of penicillin is high
Mycelial mass increases
Both (a) and (b)
pH increase

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Antibiotics
Which of the following precursor is added in the medium to get penicillin G?

Ammonium sulphate
Phenyl carbamic acid
Ammonium chloride
Phenyl acetic acid

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