Antigen
Antigen, when injected in the body activates its specific lymphocytes in the

blood circulation
draining lymph nodes
spleen lymphoid tissue
MALT (mucosa associated

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Antigen
During the lag period between antigen contact and detection of adaptive immunity,

innate immune effectors are eliminating antigen
innate immunity blocks the activation of adaptive immune effector cells
new B and T cells with the appropriate antigen specificity must be produced in the bone marrow
antigen is hidden from the immune system in macrophages

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