Antigen
Antigen, when injected in the body activates its specific lymphocytes in the

blood circulation
spleen lymphoid tissue
draining lymph nodes
MALT (mucosa associated

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Antigen
During the lag period between antigen contact and detection of adaptive immunity,

new B and T cells with the appropriate antigen specificity must be produced in the bone marrow
innate immune effectors are eliminating antigen
antigen is hidden from the immune system in macrophages
innate immunity blocks the activation of adaptive immune effector cells

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Antigen
CD antigens

function as receptors for cytokine and CAMs
are expressed on immune cells to mark them for separation
allow leukocytes to recognize antigen
are each expressed on only one cell type

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Antigen
For specific antigen recognition by T cells,

antigen exposure during T cell maturation is required
denaturation of antigen does not reduce epitope recognition
antigen is bound by a T cell membrane antibody
MHC molecules are not required

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