Antigen
A virus vaccine that can activate cytotoxic T cells must contain

live virus
virus peptides
an adjuvant to stimulate T cell division
a high dose of virus particles

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Antigen
For specific antigen recognition by T cells,

MHC molecules are not required
antigen exposure during T cell maturation is required
antigen is bound by a T cell membrane antibody
denaturation of antigen does not reduce epitope recognition

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Antigen
During the lag period between antigen contact and detection of adaptive immunity,

innate immunity blocks the activation of adaptive immune effector cells
innate immune effectors are eliminating antigen
antigen is hidden from the immune system in macrophages
new B and T cells with the appropriate antigen specificity must be produced in the bone marrow

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