Antigen
For specific antigen recognition by T cells,

denaturation of antigen does not reduce epitope recognition
MHC molecules are not required
antigen is bound by a T cell membrane antibody
antigen exposure during T cell maturation is required

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Antigen
During the lag period between antigen contact and detection of adaptive immunity,

innate immunity blocks the activation of adaptive immune effector cells
antigen is hidden from the immune system in macrophages
new B and T cells with the appropriate antigen specificity must be produced in the bone marrow
innate immune effectors are eliminating antigen

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