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DNA Structure and Replication

DNA Structure and Replication
An RNA primer is synthesized by

DNA topoisomerase
ligase
DNA helicases
primase

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DNA Structure and Replication
DNA gyrase in E. coli

can be inhibited with antibiotics
is required only at the oriC site
adds positive supercoils to chromosomal DNA
performs the same function as helicase in eukaryotes

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DNA Structure and Replication
What is the name given to the points at which a DNA helix is unwound and new strands develop?

Replication forks
Replication origins
Okazaki fragments
Leading strands

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DNA Structure and Replication
What bands will be observed in a cesium chloride gradient after two rounds of replication?

One medium band
One medium and one heavy band
One light and one medium band
One light, one medium and one heavy band

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DNA Structure and Replication
What is the main damaging effect of UV radiation on DNA?

Depurination
Dehydration
Formation of thymine dimers
Single strand break

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DNA Structure and Replication
What is the approximate percentage of repetitive DNA sequences in human DNA?

40 to 50%
20 to 30%
10 to 20%
30 to 40%

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